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п»їWhy should Crestor not be prescribed?

Do not take Crestor if you have liver disease, or if you've ever had an allergic reaction to the drug.

Also, never take Crestor during pregnancy or while breastfeeding.


Special warnings about Crestor

Use Crestor with caution if you have a history of liver problems, if you have any symptoms associated with liver disease, or if you drink large amounts of alcohol. In rare cases, cholesterol-lowering drugs like Crestor have caused liver damage. To guard against such problems, your doctor will perform blood tests before you start taking the drug and again after 12 weeks. As therapy continues, you may have your blood tested periodically or whenever the doctor increases your dose.

There is a small chance that Crestor may cause damage to muscle tissue. Be especially cautious if you have any predisposing risk factors for muscle damage, including kidney problems or an under-active thyroid, or if you're past middle age. Promptly report to your doctor any unexplained muscle pain, tenderness, or weakness, especially if you also have a fever or you just generally do not feel well.

Use Crestor with caution if you have kidney problems. Studies have shown that the drug may affect kidney function, especially at higher doses. If your doctor finds evidence of this after routine testing, you may need to have your dosage lowered.

Be sure to tell the doctor if your ancestry is Japanese or Chinese, since these groups have been known to metabolize Crestor differently than others.

Crestor may be associated with abnormal lab test results, including tests for liver and thyroid function and blood sugar levels. If you're having any lab work done, be sure to let the doctor know you're taking Crestor.

The safety and effectiveness of Crestor have not been established in children.
Possible food and drug interactions when taking Crestor

If you take Crestor with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Crestor with any of the following:

Antacids
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Cyclosporine
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Niacin
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Generic Name: Quinapril (KWIN-uh-pril)
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